human MUC7 20-Mer peptide
For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
Catalog Number: MPE0011472
Product Quantity: 5mg/20mg
Price: Varies
Availability: In Stock
Product Information
Derived from the C-terminal region (residues 32-51, where 7 out 8 basic residues are located) of MUC7 domain 1. Activity was initially reported in a previous study (Smith CJ and Bobek LA 2001 J Dent Res 80:601). Active against bacteria A. actinomycetemcomitans, E. coli, P. aeruginosa, S. mutans (cariogenic bacteria), P. gingivalis, and S. gordonii (MIC 1-4.4 uM), fungi C. albicans, C. glabrata, C. krusei, and C. neoformans CN2, and S. cerevisiae (MIC 2.4-5.8 uM) (including resistant forms of C. albicans, C. glabrata, and C, neoformans) (MIC 2.4-12.3 uM). The secondary structure prediction showed that MUC7 20-mer adopts an amphiphilic helix. The peptide is still active after removing the first eight residues (MUC7 12-mer). In saliva (proteases and ionic strength), the D-form of MUC7-12mer is more active than the L-form, although they showed similar activity in phosphate buffer (PBS) (D=L). Updated 12/2014. human MUC7 20-Mer has Antibacterial, Antifungal activity. human MUC7 20-Mer was found in Homo sapiens.
| Product Name: | human MUC7 20-Mer peptide |
| Sequence: | LAHQKPFIRKSYKCLHKRCR |
| Three letter code: | Leu-Ala-His-Gln-Lys-Pro-Phe-Ile-Arg-Lys-Ser-Tyr-Lys-Cys-Leu-His-Lys-Arg-Cys-Arg |
| Length (aa): | 20 |
| Peptide Purity (HPLC): | >95%; 98% and 99% purity available upon request |
| Quantity/Unit: | 1 Vial |
| * Optional Service: | TFA Removal Service is available upon request. |
Technical Information
| Source: | Synthetic |
| Storage Guidelines: | Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides |
| Solubility: | Soluble in water |
| Appearance: | White to off-white powder |
| Shipping: | Peptides are shipped at ambient temperature by standard shipment process. |
| About TFA salt: | Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA. TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR. TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues |
Related Products / Services
Custom Peptide Synthesis: human MUC7 20-Mer peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...
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